Series II documents Runyon's professional work with various national organizations for which she was on staff in the 1960s-1980s. These include the American Civil Liberties Union, the National Committee for a Sane Nuclear Policy, the National Conference for New Politics, and the Committee to Defend the Panthers. Later files cover consultant work Runyon did for local groups in the 1990s and 2000s, mostly doing fundraising and other writing and editing. Her papers include correspondence, flyers, financial documentation, publications, and event materials from these organizations. There are also some publications, documents, newspaper clippings, and photographs from causes and events Runyon participated in, such as the March on Washington in 1963 and resistance to the Vietnam War.