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The collection is primarily made up of notes for lectures that he gave and classes that he taught, drafts of essays and books he was working on, some books and literary journals, and some correspondence.

Papers of Stafford, reflecting a wide interest in psychedelic drugs, other drugs, and all aspects of the youth culture of the 1960s. Among the manuscript materials are drafts for chapters in his books, case histories, some correspondence, and materials showing the workings of the underground press. There are clippings, pamphlets, and books of both technical and popular interest.

Letters, reports, orders, directives, proclamations, and other official papers of two of the last Spanish Viceroys in Peru, José Fernando de Abascal y Souza (1743-1821), and Joaquín de la Pezuela (1761-1830). Most of the letters and documents are in clerical hands, with viceregal signatures and stamps, and are of a routine administrative nature. Bound in the volumes are four broadsides printed in Peru at the direction of the King of Spain. All the items originate from either Lima or Cuzco, the seat of the Spanish government. Also, one folder of notes about the volumes, primarily by Ray Trautman.

Personal, academic, and legal correspondence, manuscripts, documents, photographs, and memoranda. Among the legal files, there is particular emphasis on labor and welfare law. The files also contain materials about his judicial appointment, the American Law Institute, the Columbia University School of Law, and the Project on International Procedure. Among the major correspondents are: James A. Farley, Arthur J. Goldberg, Philip C. Jessup, Robert F. Kennedy, Harold R. Medina, James A. Pike, and Lionel Trilling

Correspondence, manuscripts, and documents relating to the printing firm of John Nichols and Son, covering a period from 1713, when the original firm of William Bowyer, the Elder (1663-1737), was burned, until the death of John Gough Nichols in 1873. The correspondence concerns primarily the social and domestic affairs of John Nichols (1745-1826) and of his family from 1766 to 1812. Scattered letters from business associates and minor authors are included, among them a group of letters from John Pridden (1758-1825), author and antiquary. The correspondence of John Bowyer Nichols (1779-1863) concerns the Nichols firm from 1799 to 1855. There are also several letters of, and relating to, William Bowyer (1699-1777), the senior partner of John Nichols. The collection also contains a volume of letters of condolence written at the time of John Nichols' death. The manuscripts in the collection consist primarily of the poetry of John Nichols, much of which was published in newspapers of the late 18th century. The manuscripts of John Bowyer Nichols concern his father and family. There are also contracts, bills, receipts, accounts, pamphlets, broadsides, engravings, and a group of 277 portraits.