A collection of manuscripts pertaining to the social and business history of the John Wyles family. The more important earlier letters in the collection, 1795-1805, indicate the commercial and speculative interest, largely in real estate, John Wyles had in the newly settled territory of the Western Reserve. The subsequent letters and manuscripts including deeds, receipts, and miscellaneous papers, are concerned with the financial and business history of the Wyles family throughout the several generations from 1800 through 1903.