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Correspondence, notes, and manuscripts including items that relate to most of Agnew's professional activities, are especially rich in materials that deal with the treatment of eye diseases during the latter half of the 19th century. An interesting sidelight of the collection is a group of finely detailed woodblocks and steel plates that Agnew used to illustrate his published articles.

A photostatic copy of the diary of Strong. The diary, running without interruption from Oct. 1835 through June 1875, contains a wealth of information about life in New York City. Its scope broadens to include the national scene with the outbreak of the Civil War. There is also a miscellaneous assortment of approximately 150 photostatic copies of personal correspondence with family and friends, correspondence during his term as treasurer of the U.S. Sanitary Commission, original drawings, caricatures and doodlings, invitations, guest lists, theater and concert programs, newspaper clippings, a family tree, and photographs. Includes typed index of Columbia references in Strong's diary.