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Manuscripts, proofs, and printed editions of Scheinfeld's books on human heredity, YOU AND HEREDITY, WOMEN AND MEN, and THE NEW YOU AND HEREDITY. Sketches and line drawings used as illustrations in the books are included. Also, manuscripts and clippings of his magazine articles; many examples of his comic strips, including "Dixie Dugan;" and correspondence and financial documents about his works.

The collection consists of the editorial and production archives of Vanguard Press: correspondence, manuscripts, contracts, memoranda, galley proofs, photographs, clippings, and printed materials. The correspondence and editorial files contain a wealth of detailed information about individual authors and the growth and development of the Press. Among the cataloged correspondents are: Nelson Algren, Saul Bellow, Stephen Vincent Benét, William Rose Benét; Phyllis Bottome; Pierre Boulle; Jocelyn Brooke; Cyril Connolly; A.J. Cronin; Nigel Dennis; John Dewey; Max Eastman; James T. Farrell; Vardis Fisher; Richard Garnett; Theodor Seuss Geisel; Louis Golding; Paul Goodman; Horace Gregory; Geoffrey Grigson; Lillian Hellman; William Heyen; Harold L. Ickes; Christopher Isherwood; Alfred Kazin; Philip Lamantia; Sinclair Lewis; Emanuel Litvinoff; Dwight Macdonald; Archibald MacLeish; Marshall McLuhan; Thomas Mann; Edgar Lee Masters; H. L. Mencken; William Meredith; Joyce Carol Oates; Katherine Anne Porter; Barbara Pym; William Sansom; William Saroyan; Ramon J. Sender; Upton Sinclair; Rex Stout; Edith Sitwell; Paul Theroux; Lionel Trilling; Harry S. Trumam; Louis Untermeyer; Eudora Welty; Richard Wilbur; and Thornton Wilder. There are some manuscripts by Bellow; Bottome; Boulle; Farrell; Grigson; Litvinoff; MacDonald; Oates; John Cowper Powys; Arthur Schlesinger, Jr.; Patrick Tanner; William Targ; Theroux; and Sitwell.