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The collection consists of speeches, reports, publications, research notes, and correspondence. The bulk of the collection relates to Wu's involvement in the American Physical Society as well as her research activities. The correspondence is chiefly professional, relating to C. S. Wu's physics research, professional commitments, appointments, meetings, conferences, and publications. Correspondence also includes letters from individuals around the world praising Wu for her accomplishments, asking advice, arranging speaking engagements, discussing administrative matters, and trading research notes, as well as information on publications and other topics. In addition, the collection contains information on Wu's involvement in the development of an affirmative action program at Columbia University in the 1970's.

Correspondence, manuscripts, and subject files on most aspects of Pegram's career. Also, a large quantity of research notes made by Lucy J. Hayner (1898-1971), Professor Emeritus of Physics at Columbia University, who was writing a history of Columbia's Physics Dept., 1905-1954, can be found in folders throughout the collection.