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The collection consists of speeches, reports, publications, research notes, and correspondence. The bulk of the collection relates to Wu's involvement in the American Physical Society as well as her research activities. The correspondence is chiefly professional, relating to C. S. Wu's physics research, professional commitments, appointments, meetings, conferences, and publications. Correspondence also includes letters from individuals around the world praising Wu for her accomplishments, asking advice, arranging speaking engagements, discussing administrative matters, and trading research notes, as well as information on publications and other topics. In addition, the collection contains information on Wu's involvement in the development of an affirmative action program at Columbia University in the 1970's.

Shirley Leon Quimby papers include correspondence, manuscripts of works by Quimby and others, notes on lectures, teaching materials, photographs of physicists, some instrument catalogs and other printed materials. Much of the material documents grant funded research directed by Quimby on CuAu. In his later years Quimby did research on the Mayan Calendar.

The Willard L. Severinghaus Papers include the personal and professional papers of Columbia University Physics professor Willard Lesly Severinghaus, as well as a small amount of material related to the extended Severinghaus family. There are also record books from the Terre Haute, Indiana German Methodist Episcopal Church where Severinghaus's father, John F. Severinghaus, was pastor.