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The collection is comprised of correspondence, manuscripts, teaching materials, conference materials, subject files, and printed items from William S. Vickrey's career as an economist. It contains published and unpublished papers illustrating his thoughts on various aspects of economic theory and their practical application. Topics discussed in these manuscripts involve macroeconomics, marginal cost pricing, microeconomics, political economy and welfare, public finance, social choice, taxation, transportation, urban economics, and related matters. The collection also has records from his tenure at Columbia University, including correspondence with his academic colleagues and participation in professional activities.